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Apr 19, 2024
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PGPM 607 EpigeneticsAlterations in structure and organization of
chromosomes and other macromolecules influence
gene expression. These physical variations can be
attributed to DNA methylation, histone
modifications, chromatin remodeling, and the
association of non-coding RNA molecules. This
course begins with a discussion of the histone
code; chromatin associated proteins, the
formation and maintenance of heterochromatin, and
diseases associated therein. This is followed by
discussions of the role of epigenetics in disease
conditions such as tumorigenesis, the onset of
certain types of neurological disorders, endocrine
and cardiovascular disorders and the current
therapies and research in this area. Credit(s): 2
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